DOHH-2 cell line is a human B-cell lymphoma cell line established from a patient with histiocytic lymphoma, which is a rare subtype of non-Hodgkin’s lymphoma. DOHH-2 cells are used in research to study the molecular mechanisms, signaling pathways, and potential therapeutic targets related to B-cell lymphomas and other hematological malignancies.

These cells provide an in vitro model system for studying the biology and pathology of human B-cell lymphomas and for screening potential therapeutic agents. They can be used in combination with other cell lines and in vivo models to generate comprehensive data on lymphoma progression, drug resistance, and potential treatment strategies.

It is important to handle and culture DOHH-2 cells using appropriate techniques and conditions to ensure their optimal growth and viability. These include maintaining the cells in suitable culture medium, providing the appropriate temperature and humidity, and regularly monitoring cell confluence and viability.