Karpas-299 cell line is a human B-cell lymphoma cell line, which was established from the biopsy of a patient with non-Hodgkin’s lymphoma, specifically diffuse large B-cell lymphoma. Karpas-299 cells are widely used in research to study the molecular mechanisms, signaling pathways, and potential therapeutic targets related to B-cell lymphomas and other hematological malignancies.
Karpas-299 cells provide an in vitro model system for studying the biology and pathology of human B-cell lymphomas and for screening potential therapeutic agents. They can be used in combination with other cell lines and in vivo models to generate comprehensive data on lymphoma progression, drug resistance, and potential treatment strategies.
It is important to handle and culture Karpas-299 cells using appropriate techniques and conditions to ensure their optimal growth and viability. These include maintaining the cells in suitable culture medium, providing the appropriate temperature and humidity, and regularly monitoring cell confluence and viability.